Reaktion #467026

ord-e246fd5d0c5a446a844aaf305ad769b7

Reaktionsgleichung

CCOC(=O)n1c(C(=O)c2cccc(S(N)(=O)=O)c2)c(N)c2ccc(Cl)cc21
3-[3-amino-6-chloro-1-(ethoxycarbonyl)indole-2-carbonyl]benzenesulfonamide
CCOC(=O)n1c(C(=O)c2cccc(S(N)(=O)=O)c2)c(N)c2ccc(Cl)cc21
3-[3-Amino-6-chloro-1-(ethoxycarbonyl)indole-2-carbonyl]benzenesulfonamide
→
Nc1c(C(=O)c2cccc(S(N)(=O)=O)c2)[nH]c2cc(Cl)ccc12
title compound
Nc1c(C(=O)c2cccc(S(N)(=O)=O)c2)[nH]c2cc(Cl)ccc12
3-(3-Amino-6-chloroindole-2-carbonyl)benzenesulfonamide

Edukte

CCOC(=O)n1c(C(=O)c2cccc(S(N)(=O)=O)c2)c(N)c2ccc(Cl)cc21
3-[3-amino-6-chloro-1-(ethoxycarbonyl)indole-2-carbonyl]benzenesulfonamide
CCOC(=O)n1c(C(=O)c2cccc(S(N)(=O)=O)c2)c(N)c2ccc(Cl)cc21
3-[3-Amino-6-chloro-1-(ethoxycarbonyl)indole-2-carbonyl]benzenesulfonamide

Reagenzien

Keine

Lösungsmittel

CC(C)O.Cc1ccccc1
2-propanol toluene

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described in step 2 of Example 1 employing 3-[3-amino-6-chloro-1-(ethoxycarbonyl)indole-2-carbonyl]benzenesulfonamide (step 1). m.p.: 125-127° C. (2-propanol/toluene)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10