Reaktion #466926

ord-1e1302b2b13b4332813e19da5f50b259

Reaktionsgleichung

CCOC(=O)n1c(C(=O)c2ccc(Cl)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-2-(4-chlorobenzoyl)-1-(ethoxycarbonyl)indole
CCOC(=O)n1c(C(=O)c2ccc(Cl)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-chlorobenzoyl)indole
→
CC(=O)Nc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12
title compound
CC(=O)Nc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12
3-Acetylamino-6-chloro-2-(4-chlorobenzoyl)indole

Edukte

CCOC(=O)n1c(C(=O)c2ccc(Cl)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-2-(4-chlorobenzoyl)-1-(ethoxycarbonyl)indole
CCOC(=O)n1c(C(=O)c2ccc(Cl)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-chlorobenzoyl)indole

Reagenzien

Keine

Lösungsmittel

CCCCCC.CCOC(C)=O
ethyl acetate hexane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-acetylamino-6-chloro-2-(4-chlorobenzoyl)-1-(ethoxycarbonyl)indole (step 1). m.p.: 175-176° C. (ethyl acetate/hexane)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10