Reaktion #466908

ord-4f27c8429c47409d87bc039b350ee713

Reaktionsgleichung

CCOC(=O)n1c(C(=O)c2ccc(OC)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole
CCOC(=O)n1c(C(=O)c2ccc(OC)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole
→
COc1ccc(C(=O)c2[nH]c3cc(Cl)ccc3c2NC(C)=O)cc1
title compound
COc1ccc(C(=O)c2[nH]c3cc(Cl)ccc3c2NC(C)=O)cc1
3-Acetylamino-6-chloro-2-(4-methoxybenzoyl)indole

Edukte

CCOC(=O)n1c(C(=O)c2ccc(OC)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole
CCOC(=O)n1c(C(=O)c2ccc(OC)cc2)c(NC(C)=O)c2ccc(Cl)cc21
3-Acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole

Reagenzien

Keine

Lösungsmittel

CCCCCC.CCO
ethanol hexane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-acetylamino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole (step 2). m.p.: 137-139° C. (ethanol/hexane)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06300363B1uspto-grants-2001_10