Reaktion #465938

Reaktionsgleichung

isatin

HCl

→

acridine acid

Lösungsmittel

KOH

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe dark green mixture was cooled
2. 2
   WaschenThe solid was washed with water
3. 3
   Sonstigeair-dried

Vorschrift

The isatin product was refluxed in 110 mL of 10% KOH solution in water over night. The dark green mixture was cooled and acidified with 400 mL of 1:1 ice/5 M HCl. The solid was washed with water and air-dried yielding the acridine acid. 1H NMR (DMSO-d6) δ 7.81-7.94 (m, 4H), 8.31-8.36 (m, 2H).

Quelle