Reaktion #465381

Reaktionsgleichung

carboxyhexacyclo[6.6.1.13,6.110,13.02,7.09,14 ]heptadecen

3,4-dihydro-2H-pyran

→

heptadecen

Lösungsmittel

—

50

tetrahydrofuran

p-toluen sulfonic acid

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas added to the solution
2. 2
   Waschenwas washed in 3% solution of Na2CO3, saturated water of salt and water in this order
3. 3
   Trocknenthe organic layer was dried with MgSO4
4. 4
   SonstigeWhen ether and residual 3,4-dihydro-2H-pyran were removed in vacuum
5. 5
   Sonstigean evaporator, we

Vorschrift

Subsequently, carboxyhexacyclo[6.6.1.13,6.110,13.02,7.09,14 ]heptadecen of 2.1 grams and 3,4-dihydro-2H-pyran of 1.71 grams were dissolved in tetrahydrofuran of 50 milli-litter, and p-toluen sulfonic acid of 0.03 gram was added to the solution. The reaction was continued at room temperature for 2 hours. The resultant material was diluted in ether of 100 milli-litter, and was washed in 3% solution of Na2CO3, saturated water of salt and water in this order, and the organic layer was dried with MgSO4. When ether and residual 3,4-dihydro-2H-pyran were removed in vacuum by using an evaporator, we obtained viscous-liquid of 12-tetrahydropyranyloxycarbonilhexacyclo[6.6.1.13,6.110,13.02,7.09,14 ]heptadecen of 2 grams.

Quelle