Reaktion #464696

Reaktionsgleichung

HCl

2-ethylimidazole

tin (II) chloride

carbonyldiimidazole

4,6-dichloro-5-nitropyrimidine

N-benzyl-2-(diethylamino)cyclohexylamine

→

4-((2-(Diethylamino)cyclohexyl)amino)-9-ethylimidazo[5,1 -h]pteridin-6(5H)-one

Reaktionsbedingungen

Vorschrift

Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with N-benzyl-2-(diethylamino)cyclohexylamine, followed by reaction with 2-ethylimidazole, reduction with tin (II) chloride, cyclization with carbonyldiimidazole and debenzylation with refluxing 5 N HCl for 3 hours.

Quelle