Reaktion #464695

Reaktionsgleichung

HCl

2-ethylimidazole

tin (II) chloride

carbonyldiimidazole

4,6-dichloro-5-nitropyrimidine

1-methyl-4-(benzylamino)piperidine

→

9-Ethyl-4-[(1-methylpiperidin-4-yl)amino]imidazo[5,1-h]pteridin-6(5H)-one

Reaktionsbedingungen

Vorschrift

Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with 1-methyl-4-(benzylamino)piperidine, followed by reaction with 2-ethylimidazole, reduction with tin (II) chloride, cyclization with carbonyldiimidazole and debenzylation with refluxing 6 N HCl for 30 minutes.

Quelle