Reaktion #464692
ord-3212f7b590b4430483b6c6024c3e6bfd
Reaktionsgleichung
2-ethylimidazole
cyclohexene
carbonyidiimidazole
4,6-dichloro-5-nitropyrimidine
1-methyl-4-(methylamino)piperidine
→
9-Ethyl-4-[(1-methylpiperidin-4-yl)methylamino]imidazo[5,1 -h]pteridin-6(5H)-one
Edukte
Reagenzien
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with 1-methyl-4-(methylamino)piperidine followed by reaction with 2-ethylimidazole, reduction with palladium on carbon and cyclohexene in refluxing ethanol, and cyclization with carbonyidiimidazole.