Reaktion #46369

ord-b9980ce2038242daa2c978af4d852940

Reaktionsgleichung

CC(C)(C)OC(=O)N1CCCCC1CN
(RS)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
CSc1nc2ncccc2o1
2-methylthio-4-azabenzoxazole
→
CC(C)(C)OC(=O)N1CCCCC1CNc1nc2ncccc2o1
title compound
CC(C)(C)OC(=O)N1CCCCC1CNc1nc2ncccc2o1
(RS) 2-(4-Azabenzooxazol-2-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester

Edukte

CC(C)(C)OC(=O)N1CCCCC1CN
(RS)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
CSc1nc2ncccc2o1
2-methylthio-4-azabenzoxazole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound (0.7 g) was prepared from (RS)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.64 g) and 2-methylthio-4-azabenzoxazole Chu-Moyer et al J. Org. Chem. (1995), 60(17), 5721-5. (0.5 g) according to the method of D30.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07741329B2uspto-grants-2010_06