Reaktion #463664

ord-82320ba8ddcd4f1ab2c6950cc6228010

Reaktionsgleichung

NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1
nicotinamide adenine dinucleotide
O=C([O-])c1cccnc1
nicotinate
O=C(O)c1cccnc1.O=C1CCC(=O)N1O
N-hydroxysuccinimide nicotinate
→
NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1.O=C1CCC(=O)N1O
N-hydroxysuccinimide nicotinamide adenine dinucleotide

Edukte

NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1
nicotinamide adenine dinucleotide
O=C([O-])c1cccnc1
nicotinate
O=C(O)c1cccnc1.O=C1CCC(=O)N1O
N-hydroxysuccinimide nicotinate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

combining nicotinamide adenine dinucleotide with NADase and NHS nicotinate, whereby NADase catalyzes an exchange of N-hydroxysuccinimide nicotinate onto nicotinamide adenine dinucleotide, yielding N-hydroxysuccinimide-nicotinamide adenine dinucleotide; and

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06020480uspto-grants-2000_02