Reaktion #463662

Reaktionsgleichung

n-BuLi

1,4-dihexyloxy-2,5-dibromobenzene

→

1,4-dihexyloxy-2-bromobenzene

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONAfter the addition
2. 2
   Sonstigewas then quenched with aq. NH4Cl at -78° C

Vorschrift

Under N2 and at -78° C., n-BuLi (23.8 mL, 2.5M in hexanes) was added, over 30 min, to a solution of 1,4-dihexyloxy-2,5-dibromobenzene (25.92 g., 59.45 mmol) in THF (150 mL). After the addition, the reaction mixture was stirred at -78° C. for 1 h and was then quenched with aq. NH4Cl at -78° C. After the usual workup, 1,4-dihexyloxy-2-bromobenzene was obtained as a pale yellow liquid (97% yield).

Quelle