Reaktion #463499

Reaktionsgleichung

water

2'-methylacetophenone

hydrobromic acid

pyridinium hydrobromide

→

title compound

2'-Methyl-2-bromoacetophenone

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted with ethyl acetate
2. 2
   WaschenThe extract was washed with water
3. 3
   Trocknena saturated sodium carbonate solution, and dried over anhydrous magnesium sulfate
4. 4
   SonstigeThe drying agent was removed by filtration
5. 5
   Sonstigethe solvent was removed under reduced pressure

Vorschrift

To a solution of 3 g of 2'-methylacetophenone in 60 ml of acetic acid was added successively 9.7 ml of 47% hydrobromic acid and 8.6 g of pyridinium hydrobromide perbromide, and the mixture was stirred at room temperature for 1 hour. The reaction mixture was poured into water and extracted with ethyl acetate. The extract was washed with water and a saturated sodium carbonate solution, and dried over anhydrous magnesium sulfate. The drying agent was removed by filtration, and the solvent was removed under reduced pressure to give 5.4 g of the title compound as a colorless oily material.

Quelle