Reaktion #4631

Reaktionsgleichung

2-benzyloxybenzylamine hydrochloride

phosgene

phosgene

→

2-benzyloxybenzyl isocyanate

Lösungsmittel

toluene

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheated at a bath temperature of 140°
2. 2
   workup.WAITboiling is continued for a further hour
3. 3
   workup.WAITThe solution is then left
4. 4
   workup.DISTILLATIONis distilled off in vacuo
5. 5
   workup.DISTILLATIONA sample of the oil remaining was distilled in a bulb tube
6. 6
   SonstigeBoiling point, bath temperature 120°/0.06 torr

Vorschrift

38.5 g of 2-benzyloxybenzylamine hydrochloride are suspended in 400 ml of distilled toluene and heated at a bath temperature of 140°. Whilst stirring, phosgene is introduced and after about 50 minutes the solution becomes clear. After a further 10 minutes, the addition of phosgene is interrupted and boiling is continued for a further hour. The solution is then left to cool a little and the toluene is distilled off in vacuo. A sample of the oil remaining was distilled in a bulb tube: Boiling point, bath temperature 120°/0.06 torr.

Quelle