Reaktion #462968

Reaktionsgleichung

potassium hydroxide

2-hydroxybenzenesulfonamide

chlorotrifluoroethylene

→

title compound

Ausbeute 60.7%

2-(2-Chloro-1,1,2-trifluoroethoxy)-benzenesulfonamide

Ausbeute 60.7%

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGAt 40° to 50° C. and while stirring
2. 2
   Sonstigewas gassed in over a period of 12 hours
3. 3
   FiltrationThe precipitate was filtered off under such and
4. 4
   Waschenwashed with acetone
5. 5
   SonstigeThe filtrate was evaporated down under reduced pressure
6. 6
   workup.STIRRINGstirred into 700 ml of water, suction
7. 7
   Filtrationfiltered
8. 8
   Waschenwashed
9. 9
   Sonstigedried

Vorschrift

At 25 bis 30° C. and while stirring, 5.9 g (0.093 mol) of 88% strength potassium hydroxide powder was added over a period of 5 minutes to a solution of 28.4 g (0.164 Mol) of 2-hydroxybenzenesulfonamide in 200 ml of acetone. At 40° to 50° C. and while stirring, 29.6 g (0.254 mol) of chlorotrifluoroethylene was gassed in over a period of 12 hours. The precipitate was filtered off under such and washed with acetone. The filtrate was evaporated down under reduced pressure, stirred into 700 ml of water, suction filtered, washed and dried. There was obtained 28.8 g (60.7%) of the title compound of m.p. 113° to 116° C.

Quelle