Reaktion #4629

Reaktionsgleichung

5-(2-bromoethoxy)salicylamide

1-(2-allyloxyphenoxy)-3-aminopropan-2-ol

→

1-(2-allyloxyphenoxy)-3-[2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino]propan-2-ol

Lösungsmittel

isopropanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeis melted in an oil bath at 100°

Vorschrift

A mixture of 6.5 g of 5-(2-bromoethoxy)salicylamide and 8.9 g of 1-(2-allyloxyphenoxy)-3-aminopropan-2-ol is melted in an oil bath at 100° and stirred for 1 hour using a magnetic stirrer. The working up is carried out analogously to Example 11 and yields 1-(2-allyloxyphenoxy)-3-[2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino]propan-2-ol having a melting point of 147°-148° (from isopropanol).

Quelle