Reaktion #461278

ord-592e86204a82466c93402b1bb0123d83

Reaktionsgleichung

O=[N+]([O-])c1cc[n+]([O-])cc1F
3-fluoro-4-nitropyridine-N-oxide
CCc1ncc[nH]1
2-ethylimidazole
O=C(n1ccnc1)n1ccnc1
carbonyldiimidazole
CCc1ncc2c(=O)[nH]c3ccncc3n12
title compound
CCc1ncc2c(=O)[nH]c3ccncc3n12
1-Ethylimidazo[1,5-a]pyrido[4,5-e]pyrazine-4(5H)-one

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepare by reaction of 3-fluoro-4-nitropyridine-N-oxide with 2-ethylimidazole followed by hydrogenation with Pd-C and cyclization with carbonyldiimidazole to provide the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05166344uspto-grants-1992_11