Reaktion #46066

Reaktionsgleichung

2b

4,4′-methylenebis(2,6-diisopropylaniline)

2-pyridinecarboxaldehyde

→

18a

Ausbeute 70.6%

bis-{-4-(pyridin-2-yl-methyleneamino)-3,5-diisopropylphenyl}-methane

Ausbeute 70.6%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturOn cooling to room temperature the suspension
2. 2
   Filtrationwas filtered
3. 3
   Waschenwashed with cold ethanol
4. 4
   Sonstigedried under reduced pressure

Vorschrift

To a suspension of 2b (1.60 g, 4.37 mmol) in absolute ethanol (10 ml) was added 2-pyridinecarboxaldehyde (1.24 ml, 13.11 mmol, 3 eq.) and two drops of formic acid. The mixture was stirred at 45° C. overnight. On cooling to room temperature the suspension was filtered, washed with cold ethanol and dried under reduced pressure to afford 18a as a yellow solid (1.68 g, 49%).

Quelle