Reaktion #46032

ord-26549ea3016a449ea28a1cf7beb47dde

Reaktionsgleichung

O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
sodium citrate
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
sodium citrate
[Cl-].[Cl-].[Mg+2]
MgCl2
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
sodium citrate
[Cl-].[Cl-].[Mg+2]
MgCl2
O=C(O)CC(O)(CC(=O)O)C(=O)O
Citric Acid

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Moreover, a sample of this concentrated solution (155 mg/ml, pH 4.5) was taken for addition of sodium citrate buffer of pH 4.5 to a foreseen final buffer concentration of 17.5 mM. But already after the addition of the first droplets (of 1 M sodium citrate buffer pH 4.5), E25 aggregated immediately and the solution became white turbid, turning soon into a white solid gel. If 1 M MgCl2 (instead of 1 M sodium citrate pH 4.5) is added to the final concentrated solution of Example 14 (to a final MgCl2 concentration of 50 mM), the solution remains clear.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07740842B2uspto-grants-2010_06