Reaktion #45986
ord-27ff517a489648c99cf4d73f62a9a386
Reaktionsgleichung
Reagenzien
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Aufarbeitung
- 1FiltrationThe reaction mixture was then filtered
- 2Sonstigeto remove the catalyst
- 3SonstigeThe solvent was removed in vacuuo
Vorschrift
The nitro intermediate (10 mmol) obtained above was dissolved in EtOAc (50 mL) and hydrogenated in the presence of 10% Pd/C (360 mg) until completion according to General Procedure H, as indicated by TLC or HPLC. The reaction mixture was then filtered to remove the catalyst. The solvent was removed in vacuuo to afford the desired 4-(6-methoxy-naphthalen-2-yloxy)aniline, which was used directly for further transformation without further purification.