Reaktion #459013

ord-95857e9e483b4e869b19e23c2aa6ed80

Reaktionsgleichung

CCC(=O)OC[C@@]12C(=CCC[C@@H]1C)CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12
1α-methyl-4-androstene-17β,19-diol
CCC(=O)OC[C@@]12C(=CCC[C@@H]1C)CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12
1α-methyl-4-androstene-17β,19-diol dipropionate
CC1=C2CC[C@@H]3[C@H](CC[C@]4(C)[C@@H](O)CC[C@@H]34)[C@@]2(CO)CCC1
4-methyl-4-androstene-17β,19-diol
→
CCC(=O)OC[C@]12CCCC(C)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](OC(=O)CC)CC[C@@H]12
4-methyl-4-androstene-17β,19-diol dipropionate

Edukte

CCC(=O)OC[C@@]12C(=CCC[C@@H]1C)CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12
1α-methyl-4-androstene-17β,19-diol
CCC(=O)OC[C@@]12C(=CCC[C@@H]1C)CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12
1α-methyl-4-androstene-17β,19-diol dipropionate
—
1α,17α-dimethyl-4-androstene-17β,19-diol
CC1=C2CC[C@@H]3[C@H](CC[C@]4(C)[C@@H](O)CC[C@@H]34)[C@@]2(CO)CCC1
4-methyl-4-androstene-17β,19-diol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Substituting 1α,17α-dimethyl-4-androstene-17β,19-diol and 4-methyl-4-androstene-17β,19-diol for the 1α-methyl-4-androstene-17β,19-diol above results in the preparation of 1α,17α-dimethyl-4-androstene-17β,19-diol dipropionate and 4-methyl-4-androstene-17β,19-diol dipropionate

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04087524uspto-grants-1978_05