Reaktion #4583

Reaktionsgleichung

3-chloroperbenzoic acid

2-allyloxyphenylsulfonamide

→

2-oxiranylmethoxyphenylsulfonamide

Ausbeute 78.0%

Lösungsmittel

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe solution is then heated
2. 2
   Temperaturto reflux for 3 hours
3. 3
   Temperaturcooled
4. 4
   Waschenwashed three times with saturated sodium carbonate solution
5. 5
   SonstigeThe organic phase is dried
6. 6
   Einengenconcentrated

Vorschrift

To a mixture of 15.3 g of 3-chloroperbenzoic acid in 270 ml of absolute methylene chloride are added 14.2 g of 2-allyloxyphenylsulfonamide over 2 minutes. The solution is then heated to reflux for 3 hours, cooled, and then washed three times with saturated sodium carbonate solution and once with water. The organic phase is dried and concentrated, affording 11.9 g of 2-oxiranylmethoxyphenylsulfonamide with a melting point of 132°-133° C.

Quelle