Reaktion #45829

Reaktionsgleichung

potassium nitrate

6-amino-3-bromo-4-fluoro-2-methylbenzonitrile

→

2-Amino-5-bromo-4-fluoro-6-methyl-3-nitrobenzonitrile

Lösungsmittel

sulfuric acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction liquid
2. 2
   workup.ADDITIONwas poured into ice
3. 3
   workup.STIRRINGstirred

Vorschrift

With cooling with ice, potassium nitrate (2.43 g, 21.8 mmol) was gradually added to a concentrated sulfuric acid (20 ml) solution of 6-amino-3-bromo-4-fluoro-2-methylbenzonitrile (I-265) (5.00 g, 21.8 mmol). After stirring for 10 minutes, the reaction liquid was poured into ice and stirred.

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