Reaktion #458233

Reaktionsgleichung

3-(3-bromo-4-trifluoromethoxyphenyl)-2,2-dimethyl-cyclopropanecarboxylic acid

thionyl chloride

→

3-(3-bromo-4-trifluoromethoxyphenyl)-2,2-dimethyl-cyclopropanecarboxylic acid-chloride

Ausbeute 93.7%

Lösungsmittel

carbon tetrachloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was then heated
2. 2
   Temperaturunder reflux for 4 hours
3. 3
   SonstigeAfter the reaction period
4. 4
   workup.DISTILLATIONexcess thionyl chloride, as well as carbon tetrachloride, were distilled off in the vacuum from a water jet

Vorschrift

9.6 g (0.027 mol) of 3-(3-bromo-4-trifluoromethoxyphenyl)-2,2-dimethyl-cyclopropanecarboxylic acid were dissolved in 100 ml of carbon tetrachloride, and 10 g of thionyl chloride were slowly added dropwise at 60° C., while stirring. The mixture was then heated under reflux for 4 hours. After the reaction period had ended, excess thionyl chloride, as well as carbon tetrachloride, were distilled off in the vacuum from a water jet. 9.4 g (93.7% of theory) of 3-(3-bromo-4-trifluoromethoxyphenyl)-2,2-dimethyl-cyclopropanecarboxylic acid-chloride were obtained as a yellow liquid.

Quelle