Reaktion #456282

ord-ee6708f3284c418fa99757b23aaba65b

Reaktionsgleichung

Cc1ccc2nc(C(=O)CC(=O)C(F)(F)F)oc2c1
1-(6-methylbenzoxazol-2-yl)-4,4,4-trifluorobutane-1,3-dione
CS(=O)(=O)c1ccc(NN)cc1.Cl
4-methylsulfonylphenylhydrazine hydrochloride
→
Cc1ccc2nc(-c3cc(C(F)(F)F)nn3-c3ccc(S(C)(=O)=O)cc3)oc2c1
6-methyl-2-[1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl]benzoxazole

Edukte

Cc1ccc2nc(C(=O)CC(=O)C(F)(F)F)oc2c1
1-(6-methylbenzoxazol-2-yl)-4,4,4-trifluorobutane-1,3-dione
CS(=O)(=O)c1ccc(NN)cc1.Cl
4-methylsulfonylphenylhydrazine hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The procedure of Example 9 was repeated using 1-(6-methylbenzoxazol-2-yl)-4,4,4-trifluorobutane-1,3-dione and 4-methylsulfonylphenylhydrazine hydrochloride as the starting materials to obtain 6-methyl-2-[1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl]benzoxazole.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06136831uspto-grants-2000_10