Reaktion #455461

Reaktionsgleichung

2-(Imidazol-1-yl)-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

→

2-(imidazol-1-yl)-6-methyl-4-(3-aminobenzylamino)-thieno-[2,3-d]-pyrimidine

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst is filtered off
2. 2
   Einengenthe solution is concentrated
3. 3
   SonstigeRecrystallization

Vorschrift

A solution of 2-(Imidazol-1-yl)-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine in methanol is hydrogenated in the presence of Raney-nickel. The catalyst is filtered off and the solution is concentrated. Recrystallization yields 2-(imidazol-1-yl)-6-methyl-4-(3-aminobenzylamino)-thieno-[2,3-d]-pyrimidine.

Quelle