Reaktion #454719

ord-39ad3a991026495f8faaf29ae9415d1f

Reaktionsgleichung

c1c[nH]cn1
imidazole
Cc1sc2ncnc(NCc3cccc([N+](=O)[O-])c3)c2c1Cl
5-chloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine
→
Cc1cc2c(NCc3cccc([N+](=O)[O-])c3)nc(-n3ccnc3)nc2s1
2-(imidazol-1-yl)-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

Edukte

c1c[nH]cn1
imidazole
Cc1sc2ncnc(NCc3cccc([N+](=O)[O-])c3)c2c1Cl
5-chloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure of Example 97, the reaction of imidazole with 5-chloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(imidazol-1-yl)-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06133271uspto-grants-2000_10