Reaktion #454660

ord-3a3ef947bf234f30a1710949a2e12ea6

Reaktionsgleichung

NCc1cccc([N+](=O)[O-])c1
3-nitrobenzylamine
FC(F)(F)c1cc2c(Cl)nc(Cl)nc2s1
2,4-dichloro-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine
→
O=[N+]([O-])c1cccc(CNc2nc(Cl)nc3sc(C(F)(F)F)cc23)c1
2-chloro-6-trifluoromethyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine

Edukte

NCc1cccc([N+](=O)[O-])c1
3-nitrobenzylamine
FC(F)(F)c1cc2c(Cl)nc(Cl)nc2s1
2,4-dichloro-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure of Example 1, the reaction of 3-nitrobenzylamine with 2,4-dichloro-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-trifluoromethyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06133271uspto-grants-2000_10