Reaktion #453632

ord-a6c7b88a312e456890a5990db3de5b79

Reaktionsgleichung

O=C(CBr)c1ccc(O)cc1
α-bromo-4-hydroxyacetophenone
CC(N)=S
thioacetamide
→
Br.Cc1nc(-c2ccc(O)cc2)cs1
4-(2-Methylthiazol-4-yl)-phenol hydrobromide

Edukte

O=C(CBr)c1ccc(O)cc1
α-bromo-4-hydroxyacetophenone
CC(N)=S
thioacetamide

Reagenzien

Keine

Lösungsmittel

ClCCl
CH2Cl2

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeas described in Preparation 48

Vorschrift

4-(2-Methylthiazol-4-yl)-phenol hydrobromide was prepared from α-bromo-4-hydroxyacetophenone and thioacetamide as described in Preparation 48; m.p. 250-251° C. (CH2Cl2).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06130217uspto-grants-2000_10