Reaktion #45268

ord-be98669f9d524fc3869fd94f06b0badf

Reaktionsgleichung

OC1(C(F)(F)F)CCNCC1
4-(trifluoromethyl)piperidin-4-ol
ClCCBr
1-bromo-2-chloroethane
→
OC1(C(F)(F)F)CCN(CCCl)CC1
1-(2-chloroethyl)-4-(trifluoromethyl)piperidin-4-ol

Edukte

OC1(C(F)(F)F)CCNCC1
4-(trifluoromethyl)piperidin-4-ol
ClCCBr
1-bromo-2-chloroethane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

A solution of 4-(trifluoromethyl)piperidin-4-ol and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-(trifluoromethyl)piperidin-4-ol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07737283B2uspto-grants-2010_06