Reaktion #45267

ord-7c8f1850eaa84f528f9c881e4274e207

Reaktionsgleichung

CC1(O)CCNCC1
4-methylpiperidin-4-ol
ClCCCBr
1-bromo-3-chloropropane
→
CC1(O)CCN(CCCCl)CC1
1-(3-chloropropyl)-4-methylpiperidin-4-ol

Edukte

CC1(O)CCNCC1
4-methylpiperidin-4-ol
ClCCCBr
1-bromo-3-chloropropane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

4-methylpiperidin-4-ol (made via literature methods) and 1-bromo-3-chloropropane are reacted using the procedure for Example OO to afford 1-(3-chloropropyl)-4-methylpiperidin-4-ol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07737283B2uspto-grants-2010_06