Reaktion #45266

ord-b9232cd563084ef09b2a44b7cef652e3

Reaktionsgleichung

CC1(O)CCNCC1
4-methylpiperidin-4-ol
ClCCBr
1-bromo-2-chloroethane
→
CC1(O)CCN(CCCl)CC1
1-(2-chloroethyl)-4-methylpiperidin-4-ol

Edukte

CC1(O)CCNCC1
4-methylpiperidin-4-ol
ClCCBr
1-bromo-2-chloroethane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

4-methylpiperidin-4-ol (made via literature methods) and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-methylpiperidin-4-ol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07737283B2uspto-grants-2010_06