Reaktion #452653

Reaktionsgleichung

2-Chloro-5-pyridinecarboxylicacid ethylester

cyclohexylamine

→

N-cyclohexylamide

title compound

2- cyclohexylamino-5-pyridine carboxylic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture heated for 6 hours at 100° in a sealed tube

Vorschrift

2-Chloro-5-pyridinecarboxylicacid ethylester (g,,5.0 mMol) was treated with 10 mMol cyclohexylamine and the mixture heated for 6 hours at 100° in a sealed tube. Preparative HPLC of the crude product gave the title compound along with equal amounts of the N-cyclohexylamide of the starting ester.

Quelle