Reaktion #452414

Reaktionsgleichung

n-butyl bromide

NaHCO3

m-aminophenol

→

3-(n-butylamino)phenol

Ausbeute 57.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture is refluxed for 5 h
2. 2
   TemperaturAfter cooling
3. 3
   Filtrationit is filtered
4. 4
   Sonstigethe solvent is removed in vacuo

Vorschrift

0.11 mol of n-butyl bromide and 0.1 mol NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-butylamino)phenol.

Quelle