Reaktion #451464

Reaktionsgleichung

biguanide

4,5,6,7-tetrahydro-2-methoxy-3H-azepine

→

2,4-diamino-6-(5-aminopentyl)-1,3,5-triazine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturunder reflux for 18 hours
3. 3
   Temperaturcooled
4. 4
   Sonstigethe solid that crystallised
5. 5
   Sonstigewas collected

Vorschrift

A mixture of biguanide (1.05 g.), 4,5,6,7-tetrahydro-2-methoxy-3H-azepine (1.27 g.) and ethanol (50 ml.) was heated under reflux for 18 hours, cooled and the solid that crystallised was collected to give 2,4-diamino-6-(5-aminopentyl)-1,3,5-triazine which was used without further purification.

Quelle