Reaktion #44974

Reaktionsgleichung

5-Aminovaleric acid

methanol

thionyl chloride

→

methyl 5-aminovalerate hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooling
2. 2
   EinengenThe reaction solution is concentrated under reduced pressure
3. 3
   Filtrationthe precipitates are collected by filtration

Vorschrift

5-Aminovaleric acid (7.35 g) is dissolved in methanol (50 ml), and thereto is added dropwise thionyl chloride (4.9 ml) under ice-cooling. The reaction solution is then warmed to room temperature and stirred for 17 hours. The reaction solution is concentrated under reduced pressure. The resulting residue is suspended in diethyl ether and the precipitates are collected by filtration to give methyl 5-aminovalerate hydrochloride (9.93 g).

Quelle