Reaktion #449656
ord-1115f63737674e86ba475dd5b5e8555d
Reaktionsgleichung
methyl 6-bromohexanoate
methyl glycine
sodium hydride
→
6-[(carboxymethyl)amino]hexanoic acid
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
In this reaction scheme, methyl 6-bromohexanoate is alkylated with methyl glycine in the presence of sodium hydride to afford the 6-[(carboxymethyl)amino]hexanoic acid. Treatment of 6-[(carboxymethyl)amino]hexanoic acid with sodium hydroxide affords the corresponding 6-[(carboxymethyl)amino]hexanoic acid disodium salt.