Reaktion #449567

Reaktionsgleichung

5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine

2-methylbenzoyl chloride

→

yellow crystals

Ausbeute 77.1%

N-[4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl)carbonyl]phenyl]-2-methylbenzamide

Ausbeute 77.1%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe product is triturated with hexane-ethyl acetate

Vorschrift

As described for Example 9, 0.942 g (3 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine is reacted with 0.52 g (3.3 mmol) of 2-methylbenzoyl chloride in 20 ml of dichloromethane. The product is triturated with hexane-ethyl acetate to give 1.0 g of yellow crystals, m.p. 198°-203° C.

Quelle