Reaktion #4475

Reaktionsgleichung

1,3-Cyclohexanedione

4-methoxyphenylhydrazine hydrochloride

→

title compound

Ausbeute 48.7%

1,2,3,9-Tetrahydro-6-methoxy-4H-carbazol-4-one

Ausbeute 48.7%

Lösungsmittel

ethanol

water

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturat reflux for 14 h
2. 2
   TemperaturOn cooling to ambient temperature
3. 3
   Sonstigeto give a solid, which
4. 4
   Sonstigewas dried in vacuo

Vorschrift

1,3-Cyclohexanedione (8 g) was added to a solution of 4-methoxyphenylhydrazine hydrochloride (10 g) in ethanol (350 ml) and water (70 ml). The resulting solution was stirred at room temperature for 3 h and then at reflux for 14 h. On cooling to ambient temperature, the reaction mixture was poured into water (3 l) to give a solid, which was dried in vacuo to give the title compound, (6.0 g) m.p. 279°-279.5°.

Quelle