Reaktion #4473

Reaktionsgleichung

product

1,3-Cyclohexanedione mono(4-bromophenylhydrazone)

water

→

title compound

6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was cooled
2. 2
   Filtrationthe resulting solid filtered off
3. 3
   Sonstigedried (0.95 g)
4. 4
   SonstigePurification by flash chromatography (E)

Vorschrift

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

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