Reaktion #44675

Reaktionsgleichung

3-amino-1,2-benzisoxazol-4-ol

3,4-difluoronitrobenzene

potassium carbonate

→

4-(2-Fluoro-4-nitrophenoxy)-1,2-benzisoxazole-3-amine

Lösungsmittel

dimethylformamide

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe precipitate is filtered off
2. 2
   SonstigeThe product is dried under high vacuum

Vorschrift

94.37 mg (0.63 mmol) of 3-amino-1,2-benzisoxazol-4-ol (from example V), 100 mg (0.63 mmol) of 3,4-difluoronitrobenzene and 95.56 mg (0.69 mmol) of potassium carbonate are suspended in 3 ml of anhydrous dimethylformamide and stirred at room temperature for 16 hours. The reaction solution is then diluted with water, and the precipitate is filtered off. The product is dried under high vacuum.

Quelle