Reaktion #44560

Reaktionsgleichung

2,6-dichloropyrazine

3-phenyl-phenol

→

title compound

Ausbeute 98.0%

2-Chloro-6-(3-phenyl-phenyl-oxy)-pyrazine

Ausbeute 98.0%

Lösungsmittel

AcOEt

cyclohexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeMethod DD (reaction time: 20 hours)

Vorschrift

Using Method DD (reaction time: 20 hours) with 2,6-dichloropyrazine (200 mg, 1.34 mmol) and 3-phenyl-phenol (268 mg, 1.49 mmol), and purification by column chromatography (AcOEt:cyclohexane, 1:2), the title compound was obtained (370 mg). Yield: 98%. 1H NMR (250 MHz, DMSO-d6) δ 7.35-7.72 (m, 9H, Harom), 8.53 (s, 1H, HPz 5), 8.59 (s, 1H, HPz 3). m/z: 283.1 [(M+H)+, calcd for C16H11ClN2O 282.1].

Quelle