Reaktion #444014

Reaktionsgleichung

1-bromonaphthalene

HCl

→

18

Ausbeute 184.8%

2-(1-Naphthyl)toluene

Ausbeute 184.8%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigedid not exceed 50° C
2. 2
   TemperaturThe mixture was subsequently refluxed for a further 3 hours
3. 3
   Sonstigethe phases were separated
4. 4
   FiltrationFiltration through silica gel (hexane)

Vorschrift

The Grignard solution was subsequently added dropwise to a solution of 118 g (0.57 mol) of 1-bromonaphthalene and 3.5 g of bis(triphenylphosphine)nickel dichloride in 800 cm3 of toluene at such a rate that the internal temperature did not exceed 50° C. The mixture was subsequently refluxed for a further 3 hours, 500 ml of 10% strength aqueous HCl were added, the phases were separated, and the organic phase was freed from solvent in vacuo. Filtration through silica gel (hexane) gave 115 g (92%) of 18 as a colorless oil.

Quelle