Reaktion #44375

Reaktionsgleichung

Pinacol

[5-chloro-2-(phenylmethoxy)phenyl]-boronic acid

pinacol

→

2-[5-chloro-2-(phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Lösungsmittel

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGstirred for a further 24 h
2. 2
   FiltrationThe sieves were filtered
3. 3
   Waschenthe filtrate was washed with water and brine
4. 4
   Trocknendried (MgSO4)
5. 5
   Einengenconcentrated in vacuo

Vorschrift

Pinacol (3.24 g) was added to a solution of [5-chloro-2-(phenylmethoxy)phenyl]-boronic acid (6 g) in diethyl ether, and stirred for 24 h. 4 A molecular sieves and pinacol (1.5 g) were added, stirred for a further 24 h. The sieves were filtered and the filtrate was washed with water and brine, then dried (MgSO4) and concentrated in vacuo. Yield 6.8 g.

Quelle