Reaktion #44355

ord-a37936cdbea845e78e095808545a213f

Reaktionsgleichung

CC1(C)OB(c2cc(Cl)ccc2O)OC1(C)C
product
CC1(C)OB(c2cc(Cl)ccc2O)OC1(C)C
4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
C[C@@H](O)C(=O)OC(C)(C)C
tert-butyl (R)-(+) lactate
→
C[C@H](Oc1ccc(Cl)cc1B1OC(C)(C)C(C)(C)O1)C(=O)OC(C)(C)C
subtitle compound
C[C@H](Oc1ccc(Cl)cc1B1OC(C)(C)C(C)(C)O1)C(=O)OC(C)(C)C
1,1-Dimethylethyl 2-[4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-(2S)-propanoate

Edukte

CC1(C)OB(c2cc(Cl)ccc2O)OC1(C)C
product
CC1(C)OB(c2cc(Cl)ccc2O)OC1(C)C
4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
C[C@@H](O)C(=O)OC(C)(C)C
tert-butyl (R)-(+) lactate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The subtitle compound was prepared by the method of Example 2 step a) using the product from step e) and tert-butyl (R)-(+) lactate.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07737135B2uspto-grants-2010_06