Reaktion #44233

Reaktionsgleichung

methylhydrazine

ethyl pyruvate

MgSO4

→

desired product

Ausbeute 94.0%

ethyl 2-(2-methylhydrazono)propanoate

Ausbeute 94.0%

Lösungsmittel

CHCl3

CHCl3

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe reaction mixture was filtered
2. 2
   EinengenThe filtrate was concentrated under reduced pressure

Vorschrift

To a suspension of ethyl pyruvate (37.8 mL, 338 mmol) and MgSO4 (40.8 g, 339 mmol) in CHCl3 (500 mL) was added a solution of methylhydrazine (18.0 mL, 332 mmol) in CHCl3 (100 mL) at 0° C. The reaction mixture was warmed to room temperature. After stirring for 24 hours at room temperature, the reaction mixture was filtered. The filtrate was concentrated under reduced pressure to give 44 g (94%) of the desired product that was used directly without further purification.

Quelle