Reaktion #44042

ord-07d46a30f2414cbe854675dced3689b0

Reaktionsgleichung

CCOC(=O)[C@@H]1Cc2[nH]ncc2[C@H](C(=O)OCC)N1S(=O)(=O)c1ccc(Cl)cc1
cis-diethyl 5-(4-chlorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-4,6-dicarboxylate
[BH4-].[Li+]
LiBH4
→
O=S(=O)(c1ccc(Cl)cc1)N1[C@H](CO)Cc2[nH]ncc2[C@@H]1CO
cis-(5-(4-Chlorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-4,6-diyl)dimethanol

Edukte

CCOC(=O)[C@@H]1Cc2[nH]ncc2[C@H](C(=O)OCC)N1S(=O)(=O)c1ccc(Cl)cc1
cis-diethyl 5-(4-chlorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-4,6-dicarboxylate
[BH4-].[Li+]
LiBH4

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared by reduction of cis-diethyl 5-(4-chlorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-4,6-dicarboxylate using LiBH4 as shown in Example 14.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07732609B2uspto-grants-2010_06