Reaktion #43810

Reaktionsgleichung

product

(4-tert-Butoxycarbonylamino-2-nitro-phenylamino)-acetic acid tert-butyl ester

→

sub-title compound

(2-Amino-4-tert-butoxycarbonylamino-phenylamino)-acetic acid tert-butyl ester

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe reaction was filtered over celite and
2. 2
   Einengenconcentrated to dryness

Vorschrift

The product of step b.) (2.0 g, 5.45 mmol) was stirred with 3% Pd/C (200 mg) in ethanol (20 mL) under H2 (1 atm) for 90 minutes. The reaction was filtered over celite and concentrated to dryness to give the sub-title compound as a brown oil. This compound was used in crude form without purification. MS: ESI (positive): 338 (M+H).

Quelle