Reaktion #436639

Reaktionsgleichung

5-(3-bromophenyl)-2H-tetrazole

(4-bromomethylphenoxy) acetic acid tert-butyl ester

→

oil

Ausbeute 84.6%

{4-[5-(3-bromophenyl)tetrazol-2-ylmethyl]phenoxy}acetic acid tert-butyl ester

Ausbeute 84.6%

Reaktionsbedingungen

Vorschrift

This reaction was carried out as described in Example D2, Step (a) using 5-(3-bromophenyl)-2H-tetrazole (0.87 g, 2.89 mmol) and (4-bromomethylphenoxy) acetic acid tert-butyl ester (0.50 g, 2.22 mmol) in place of (4-bromo-methylbenzyl) phosphonic acid dimethyl ester. This afforded 0.85 g of light oil (84.6% yield) NMR (CDCl3); 8.28 (s, 1H), 8.07–8.05 (d, 1H), 7.58–7.55 (d, 1H), 7.38–7.31 (m, 3H), 6.90–6.88 (d, 2H), 5.72 (s, 2H), 4.50 (s, 2H), 1.48 (s, 9H)

Quelle