Reaktion #434367

ord-aaa8821a294b48c68a5b09940712095c

Reaktionsgleichung

Fc1ccc(-c2csc3cc(OCCCCBr)ccc23)cc1
6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene
CCNCCOC
N-(2-methoxyethyl)ethylamine
CCN(CCCCOc1ccc2c(-c3ccc(F)cc3)csc2c1)CCOC
Ethyl-{4-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-methoxy-ethyl)-amine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and N-(2-methoxyethyl)ethylamine were converted to yield Ethyl-{4-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-methoxy-ethyl)-amine as colorless oil, MS: 402 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07173043B2uspto-grants-2007_02