Reaktion #434364

ord-b4066c00882a4c81a3137d899384fa2f

Reaktionsgleichung

Fc1ccc(-c2csc3cc(OCCCCBr)ccc23)cc1
6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene
CNCCO
2-(methylamino)ethanol
CN(CCO)CCCCOc1ccc2c(-c3ccc(F)cc3)csc2c1
2-({4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-methyl-amino)-ethanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and 2-(methylamino)ethanol were converted to yield 2-({4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-methyl-amino)-ethanol as colorless oil, MS: 374 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07173043B2uspto-grants-2007_02